Biospecimens from MURDOCK Study Help Accelerate Heart Failure Discovery

Samples and data from the MURDOCK Study — the groundbreaking community-based biorepository at Duke Kannapolis — helped to accelerate a recent heart failure discovery by Duke University researchers.

A Duke Pathology research team in Durham led by Salvatore Vincent Pizzo, MD, PhD used biospecimens and more than 13 years of corresponding data from 690 MURDOCK Study participants to determine that serum pro\N\cadherin is an early marker for heart failure. The discovery has the potential to identify patients who would benefit from intervention before they show signs of disease, as reported in the Journal of the American Heart Association.

The Duke Clinical and Translational Science Institute (CTSI) is making thousands of biospecimens and associated clinical outcomes data available to all Duke researchers through the MURDOCK Biorepository Transformation Initiative. Duke Kannapolis is part of the CTSI and directed by Svati H. Shah, MD, MHS.

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