Research biobanks and other human research studies that collect and analyze DNA are increasingly confronted with the question of whether and how to return actionable genomic results to individual participants …
In the race to harness medical data for artificial intelligence tools and personalized health care, a new study shows how easily unintentional design bias can affect those efforts. It also …
The success of biobanking is directly linked to the willingness of people to donate their biological materials for research and storage. Ethical issues related to patient consent are an essential …
An association between diabetes mellitus (DM), especially, new-onset DM (NODM), and pancreatic ductal adenocarcinoma (PDAC) is known; others have constructed polygenic risk scores (PRS) related to PDAC risk. An independent …
Myopia, or short-sightedness, is a significant global health problem estimated to affect 1406 million people (about 23% of the world’s population) as of 2000. And if you get the sense that there …
The biobanks have developed rapidly. They typically aggregate genetic information such as WGS (whole genome sequencing), WES (whole exome sequencing), and SNP (single nucleotide polymorphisms) with a range of other …
In vitro cell culture models are indispensable tools for translational research, but the biological relevance of 2-D cell lines is limited by reduced cell-to-cell interactions compared to original tissue niches. …
Chen Liu, MD, Ph.D., Chair of Yale Pathology, is leading an effort at Yale School of Medicine (YSM) to establish an institutional biorepository for the coordinated collection of tissue, plasma, …
In biomedical research, ‘ethics’ is often approached as an administrative task in which biobanks agree to abide by a series of risk mitigation regulations mandated to them by an authority. …
The quality of biospecimens stored in a biobank depends tremendously on the technical personnel responsible for the processing, storage, and release of biospecimens. Adequate training of these biobank employees would …