Hubrecht Institute in Collaboration with Erasmus MC University Created Organoid Biobank to Study SARS-CoV-2 Genes

A team from the Hubrecht Institute in collaboration with Erasmus MC University, both the Netherlands, have developed an organoid biobank of mutant intestinal organoids to investigate the genes responsible for the spread of SARS-CoV-2 infection, thereby uncovering potential new therapeutic targets.Previously, studies used the cell lines of animals, most importantly the African green monkey, to identify therapeutic targets for the novel coronavirus. These cell lines are easy to work with, however do not fully recapitulate the biology of human cells that are targets of SARS-CoV-2.

The findings were published in Nature Communications.

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