Abstract: The Colorado Center for Personalized Medicine (CCPM) Biobank, a partnership between UCHealth and the University of Colorado Anschutz Medical Campus, has hit an incredible milestone, returning 1 million pharmacogenetic results. By analyzing how genes influence drug responses, the biobank helps explain why some treatments work for certain people while others cause side effects. With samples from over 92,000 Coloradans, this has become one of the nation’s largest biobanks, fueling research into personalized medicine. The insights include five newly identified genes that interact with common drugs like codeine, tramadol, metoprolol, and Zofran, enabling safer prescriptions and better health outcomes.
The real-world impact is profound. UCHealth patient Jim Jensen, who once suffered severe reactions to medication, received biobank results that helped his care team adjust his treatments safely and effectively. Beyond drug response, the biobank has also returned results on hereditary cancer, heart disease, and rare illness risks to over 1,000 families. With its mission to ensure the right drug at the right dose the first time, the CCPM biobank is transforming healthcare by reducing trial-and-error prescribing and empowering patients to understand their genetic profiles. This milestone marks a leap forward in precision medicine and preventive healthcare for Coloradans and beyond.
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