Organoids are a new type of 3D model for tumor research, which makes up for the shortcomings of cell lines and xenograft models, and promotes the development of personalized precision medicine. Long-term culture, expansion and storage of organoids provide the necessary conditions for the establishment of biobanks.
Patient-derived tumor organoids (PDTOs) can better summarize the key characteristics and functions of the parental tumor, ushering in a new era of precision medicine. At present, organoid biobanks of various tumors have been established, which provide reliable models for basic and clinical researches. In the future, solving the uniformity of organoid technical standards and a good quality supervision system is crucial to the establishment of a safe, accurate and convenient PDTO biobank, which should attract extensive attention from researchers.
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